Hi Devin,
In a short answer, yes. Any two part clear epoxy resin should work for your purpose. There are a couple of caveats though.
If the acrylic is flexible enough, it may cause the resin to crack or pop off. If I were doing to do this, I wouldn’t want the acrylic to be able to move.
If the acrylic is thin, the heat from the resin curing may cause it to warp depending on how much you use.
Does this help at all?